PLATFORM FOR GENOMIC ANNOTATION AND RETROSPECTIVE ANALYSIS OF AML COHORTS
- Clinical development
- AML
- Targeted therapy
- Immunotherapy
- Clinical research (TRL 6-8)
Retrospective analyses of patient data from the Hauts de France AML Observatory.
The Hauts-de-France Observatory gathers initial and follow-up clinical and biological data on adult patients with AML diagnosed in clinical hematology centers in the Hauts-de-France region. In 2022, this observatory included data on around 2,500 patients.
Description
Scope of research activities
Clinical research into AML pathology, with the aim of improving patient care and quality of life:
- Non-interventional clinical research
Role
- Provision of clinical and biological data
- Participation in the analysis of extracted data
Infrastructure
Analysis platforms:
- Database / eCRF
Models:
- Primary cells from clinical study patients
Technical personnel:
- 2 clinical research associates
Specifications
The platform
Platform for retrospective analysis of AML observatory data:
Studies
Data study
- Frequency of a clinical or biological parameter
- Study of a population defined according to clinical, biological or demographic criteria
Examples of partnerships
Establishment of a validation cohort for AML in elderly adult - The study aimed to establish a cohort of patients with the same characteristics as those included in the ALFA-1200 protocol in order to validate a prognostic score based on genetic alterations.
Partner: ALFA Group
Terms
- Clinical research project with industrial sponsoring
- Partnership agreement with study sponsor